2009 Edward E Smissman Award. Pharmaceutical "gold" from neurostabilizing agents: topiramate and successor molecules

J Med Chem. 2009 Jun 11;52(11):3431-40. doi: 10.1021/jm900141j.
No abstract available

Publication types

  • Historical Article

MeSH terms

  • Animals
  • Anticonvulsants / chemical synthesis
  • Anticonvulsants / therapeutic use
  • Chemistry, Pharmaceutical / history
  • Fructose / analogs & derivatives*
  • Fructose / chemical synthesis
  • Fructose / therapeutic use
  • Fructose-Bisphosphatase / antagonists & inhibitors
  • History, 20th Century
  • Humans
  • Hypoglycemic Agents / chemical synthesis
  • Neuroprotective Agents* / chemical synthesis
  • Neuroprotective Agents* / therapeutic use
  • Topiramate

Substances

  • Anticonvulsants
  • Hypoglycemic Agents
  • Neuroprotective Agents
  • Topiramate
  • Fructose
  • Fructose-Bisphosphatase